Research

Ridhi is an avid independent researcher with an interest in computer science and vaccine design. She strongly believes that AI has the power to revolutionize the healthcare field! Ridhi's full research portfolio can be accessed at: https://drive.google.com/drive/folders/1m0Kbs9riWkK1nMWWLWrlMIq5O6VcuOcc?usp=sharing

mRNA Vaccines for Global Health Threats

Ridhi devised a method to develop mRNA vaccines for pathogens based just off of their genome sequences. Her technique is 9 times faster than Moderna and led her to develop the world's first vaccines for MERS (COVID relative), Marburg (world's deadliest virus), and glioblastoma (single deadliest brain cancer). Her work has been accepted for publication in several PhD level conferences (CSHL Immunoengineering, CSHL Biology of Genomes, ISCB-Africa, and more) with recognition from national science fairs and business events.

Oncolysis

Ridhi founded a cancer mRNA vaccine design startup dedicated to creating mRNA solutions for the world's deadliest cancers. Beyond glioblastoma, Ridhi has created vaccine candidates for non small cell lung cancer and pancreatic adenocarcinoma. For this work, she was recognized as 1 of just 2 international recipients of the Gore Innovation Prize (prize for technology making an impact) at the Diamond Challenge. Harvard Medical School has shown interest in using her research as a large scale mRNA design tool.

View the press release here: https://horn.udel.edu/student-changemakers-shine-at-limitless-world-summit

See Ridhi's patent filing here: https://drive.google.com/drive/folders/1ZtTvNwbcYHYpEA6CooTOZSwLG4Xh_jfF?usp=sharing

Her preprint can be accessed here: https://www.techrxiv.org/users/961970/articles/1330943-genomi-a-breakthrough-system-for-robust-genetic-interaction-discovery-revolutionizing-biological-insight-for-the-discovery-of-novel-gene-regulatory-networks-and-application-of-gene-regulatory-networks-to-industrial-level-genetic-engineering-and-vaccine-development

GENOMI

Ridhi devised a method to map regulatory networks in genomes for enhanced application to commercial genetic engineering. Ridhi developed GENOMI (gene expression network optimized mutual information), a patent pending genomics pipeline to map regulatory networks from gene expression data alone. Ridhi discovered the most complete regulatory network of E. coli, the bacterium most commonly used in genetic engineering applications. Her work enables regulatory inference as a commercial optimization technique for the first time, enabling breakthroughs in the construction of recombinant vaccines, drugs, and environmentally sustainable fuel solutions.

Cryptosporidium

Ridhi had the amazing opportunity to collaborate with Dr. Carol Gilchrist at UVA to apply her revolutionary mRNA technology to efforts dedicated to developing a vaccine for Cryptosporidium, a parasite causing deadly gastroenteric infection in Bangladeshi children.

Lassa Fever Research With the US Army

Her most recent project, Ridhi is applying Vaccelerate to engineer a vaccine for Lassa Fever (a deadly African Virus) with the US Army Medical Research Infectious Disease Laboratory. In collaboration with Dr. Brian Carey, Ridhi is being funded to help protect the US against this bioterrorism threat with her technology.

RespiraAI

Her first foray into computational research, Ridhi developed RespiraAI in collaboration with BetterMindLabs. RespiraAI scans X-rays and CTs to diagnose patients with lung disease and classify the kind of lung disease they have. It's built specifically for low income communities where such diseases are the most prevalent.

View the IEEE publication here: https://ieeexplore.ieee.org/document/10984767

Post-Doc

Conference Invites

Invited to share insights at prestigious conferences like IEEE IATMSI, ISCB-Africa, GLBIO, ISMB, CSHL Immunoengineering, and more. Engaged with Harvard Medical School and UPenn Weissman Lab.